Graft Rejection Rate and Graft Failure Rate of Penetrating Keratoplasty (PKP) vs Lamellar Procedures: A Systematic Review

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Graft Rejection Rate and Graft Failure Rate of Penetrating Keratoplasty (PKP) vs Lamellar Procedures: A Systematic Review

PURPOSE The aim of our investigation was to conduct a quantitative meta-analysis of the present world literature comparing the major surgical outcomes of penetrating keratoplasty (PKP) to lamellar procedures. Our goal is that clinicians, eye bank administrators, and health policy makers will be able to utilize this study in implementing decisions in regards to corneal transplantation. METHODS...

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Risk Factors for Failure of Keratoplasty in Keratoconus: Penetrating vs. Deep Anterior Lamellar Keratoplasty

Purpose: To determine the etiologic factors on rejection and failure rates and ocular surface changes after corneal transplantation by either DALK or PKP, in cases of keratoconus (KCN). Methods: In this cross-sectional study, considering the existing data, patients with keratoconus referring to Labbafinejad Medical Center from 2006 to 2016, who underwent corneal transplantation, were enrolled a...

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Topical Bevacizumab Therapy in Graft Rejection After Penetrating Keratoplasty

Neovascularization is defined as formation of new vessels from vascular endothelial cells derived from existing blood vessels. These new immature vessels are friable. They have increased permeability, lack structural integrity, and can result in lipid deposition and corneal opacities. Ultrastructurally, corneal neovascularization is characterized by vessels encroaching through separated stromal...

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Prognostic factors for corneal graft recovery after severe corneal graft rejection following penetrating keratoplasty

BACKGROUND To investigate the outcome and prognostic factors for corneal graft recovery after severe corneal graft rejection following penetrating keratoplasty (PKP) treated with topical and systemic steroids. METHODS Fifty-eight eyes in 58 patients with severe corneal graft rejection following PKP were treated with topical and systemic steroids. Factors affecting the reversibility and mainte...

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Disposable graft splint in penetrating keratoplasty.

Jones and Rice (I968) have demonstrated experimentally that the endothelium of the donor corneal disc may be subjected to considerable mechanical trauma during penetrating keratoplasty by the more commonly used techniques. From these experimental observations they have developed a method in which the corneal disc is sutured over a cushion of air, thus obviating much of the endothelial trauma in...

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ژورنال

عنوان ژورنال: PLOS ONE

سال: 2015

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0119934